A biochanin-enriched isoflavone from red clover lowers LDL cholesterol in men
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چکیده
منابع مشابه
The red clover (Trifolium pratense) isoflavone biochanin A inhibits aromatase activity and expression.
Biochanin A is an isoflavone isolated from red clover (Trifolium pratense), and is a commercially available nutraceutical for women suffering from postmenopausal symptoms. Isoflavones resemble the structure of oestrogen, and display agonistic and antagonistic interactions with the oestrogen receptor. Overexposure of oestrogen is a major contributing factor in the development of breast cancer, a...
متن کاملVariable isoflavone content of red clover products affects intestinal disposition of biochanin A, formononetin, genistein, and daidzein.
BACKGROUND Marketed red clover (Trifoleum pratense) products use a wide variety of labels, and the isoflavone content from the label is ambiguous. MATERIALS AND METHODS In the present study, we analyzed the content of various isoflavone products, and determined (1) the content and (2) how the sample matrix of red clover products affects the intestinal disposition of main isoflavones within it...
متن کاملPlant sterol ester–enriched spread lowers plasma total and LDL cholesterol in children with familial hypercholesterolemia1,2
Background: Naturally occurring plant sterol esters (SEs) favorably affect serum cholesterol concentrations in humans and could aid in the treatment of children with familial hypercholesterolemia (FH). Objective: We studied the effect of SE-enriched spread on serum lipids, lipoproteins, carotenoids, fat-soluble vitamins, and physiologic variables in children with FH aged 7–12 y. Design: In a ra...
متن کاملPlant sterol ester-enriched spread lowers plasma total and LDL cholesterol in children with familial hypercholesterolemia.
BACKGROUND Naturally occurring plant sterol esters (SEs) favorably affect serum cholesterol concentrations in humans and could aid in the treatment of children with familial hypercholesterolemia (FH). OBJECTIVE We studied the effect of SE-enriched spread on serum lipids, lipoproteins, carotenoids, fat-soluble vitamins, and physiologic variables in children with FH aged 7-12 y. DESIGN In a r...
متن کاملOat-bran cereal lowers serum total and LDL cholesterol in hypercholesterolemic men.
Oat bran lowers serum lipid concentrations in healthy and hyperlipidemic subjects. To determine the effects of a ready-to-eat oat-bran cereal on lipid concentrations, we fed control (corn flakes) and oat-bran cereal diets for 2 wk to 12 men with undesirably high serum total-cholesterol concentrations. Subjects were randomly assigned to one of the two diets upon admission to the metabolic ward. ...
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ژورنال
عنوان ژورنال: European Journal of Clinical Nutrition
سال: 2004
ISSN: 0954-3007,1476-5640
DOI: 10.1038/sj.ejcn.1601796